REVISTA PORTUGUESA DE

MEDICINA
INTENSIVA

YEAR 6 * NUMBER 7 * JUNE 1997

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Noninvasive ventilation in post extubation acute respiratory failure

Teresa Honrado, J. Chaves Caminha, Álvaro M. Silva, Sofia Esperança, A. Paes Cardoso, Fernando Rua

Abstract:
Several studies reported the efficacy of Noninvasive Ventilation (NIV) in avoiding reintubation in patients who developed acute respiratory failure shortly after extubation. In this study NIV was administered to 20 patients with different diagnoses who experienced respiratory distress after extubation. All of them, where considered weaned and met the extubation criteria. NIV was delivered by nasal mask connected to a BiPAP ventilator (Respironics Inc.).
NIV was successful in avoiding tracheal reintubation in 12 patients (60% rate of success), and significantly reduced the length of ICU stay of the patients successfully ventilated with NIV, when compared with those who failed. There was no differences in the diagnoses related to ARF between the two groups. Data analysis showed that there was no significant differences at base-line arterial blood gas levels before initiating NIV and these values did not predict the response to NIV.
We concluded that application of NIV is effective in a selected group of patients who dveloped ARF shortly after extubation, reducing the rate of tracheal reintubations and the length of ICU stay.
Keywords: Noninvasive Ventilation, Postextubation Acute Respiratory Failure, BiPAP, Prediction of Success.

Fiberoptic bronchoscopy in ICU patients

A. Oliveira Meleiro, A. C. Duarte, P. Cravo, A. Mineiro, M. G. Freitas

Summary:
We analysed 463 fiberoptic bronchoscopies which were performed on patients admitted to our ICU from 1992 to 1995, according to the American Thoracic Society Guidelines.
The results obtained confirmed the therapeutic and diagnostic relevance of fiberoptic bronchoscopy and showed the safety of the technique.
Keywords: Fiberoptic Bronchoscopy in ICU´s: Fiberoptic Bronchoscopy in ventilade patients.

Transbronchial biopsy during mechanical ventilation

J. Chaves Caminha, Álvaro M. Silva, F. Rua

Summary:
Patients with progressive or persistent pulmonary infiltrates which require mechanical ventilation and who are not clinically improving their condition, may require lung tissue examination to establish a specific diagnosis. Since 1994 we performed 4 transbronchial biopsies (TBB) in patients with these conditions. we decide to perform TBB to increase the diagnostic yield of flexible fiberoptic bronchoscopy in conjunction with the bronchoalveolar lavage (BAL). TBB was diagnostic in three patients, and in one additional case the diagnostic was made from the accompanying liquid of bronchoalveolar lavage. We had one tension pneumothorax as a complication to TBB. No fatalities were attributable to TBB. In these hemodynamically stable patients requiring mechanical ventilation for diffuse lung disease, TBB was performed safely and provided important data, which showed that the diagnostic yeld of flexible fiberoptic bronchoscopy increased and the therapeutic management was modified. However BAL remains the first approach.
Keywords: Fiberoptic Bronchoscopy, Transbronchial Biopsy, Bronchoalveolar Lavage, Mechanical Ventilation.

Nutrition in renal failure

Anabela Rodrigues, Isabel Fonseca, Aníbal Marinho

Summary:
With the improvement of the methods of hemodynamic resuscitation and cardiorespiratory support, there has been a progressive reduction in the incidence of acute renal failure (IRA) in the ICU´s. However, the associated mortality rate has remained high even though progress has continued to be made in both conventional hemodyalisis and in the new thecniques of renal replacement therapy.
Nowadays it is known undernutrition is associated with many of the factors which give rise to the occurrence of acute renal failure, or a sharp reduction in the renal function of patients with chronic renal failure. The authors present a review concerning about nutritional support of patients with renal failure.
Keywords: nutrition, renal failure, albumine, hemodyalisis, renal replacement therapy.

Continuous renal replacement therapy: indications and pratice

Rui Castro, João Pedro S. Pimentel, Aníbal Marinho, Manuela Sousa, Anselmo Madureira, António Paes Cardoso, Serafim Guimarães

Summary: Continuous Renal Replacement Theraphy (CRRT) is a major tool to any modern Intensive Care Unit. Its application has been extended from cases of acute renal failure with hemodinamic instability and toxins depuration to severe pathologies such as A.R.D.S. (Adult Respiratory Distress Syndrome) and Multiorgan Failure (MOF). The methods available for its implementation are diverse and continually being developed. Continuous Venovenous Hemofiltration allows a steady and rapid blood flow which ensures a greater ultrafiltration rate. The latter could be, as some authors state, directly related with the survival of some critical care patients on CRRT (eg. septic shock patients).
These therapies largely depend on nurse team skills and obviously require specific preparation and continuous care.
We will address and discuss the present possible applications and tools of CRRT. We will also present, briefly, the most frequent complications and the necessary pharmacological adaptations.
Keywords: continuous renal replacement therapy, venovenous hemofiltration, venovenous hemodiafiltration, arteriovenous hemofiltration, arteriovenous hemodiafiltration, acute renal failure, multiorgan failure.

Cerebral salt wasting syndrome: a case report

Manuela Fera, Rosa Mendes, João Alcântara, Rui Sérgio, Resina Rodrigues

Summary:
Hyponatremia is frequently seen in neurosurgical patients and is often attributed to inappropriate secretion of antidiuretic hormone. A number of studies in recent years have shown that hyponatremia in many patients with intracranial disease may actually be caused by cerebral salt wasting, in which a renal loss of sodium leads to hyponatremia and a decrease in extracellular fluid volume. The appropriate treatment of cerebral salt wasting, (fluid and salt replacement), is opposite from the usual treatment of hyponatremia caused by inappropriate secretion of antidiuretic hormone.
The authors have made a review of the most recent published literature about cerebral salt wasting syndrome.
Keywords: Neurologic disease, polyuria, natriuresis, hyponatremia, SIADH, CSW.

Vasodilators in pediatric septic shock: a case report

Augusto Ribeiro, Dulce Rainho, Filipe Almeida, José Aparício, Teresa Cunha Mota, José Carvalho, Emídio Carreiro, L. Almeida Santos

Summary:
Septic shock continues to be a serious clinical process with a high mortality and morbidity rate, in spite of the recent advances in the understanding of the it´s pathogenesis, pathophysiology and new therapeutic strategies.
Treatment with vasodilator drugs may be required if tissue perfusion continues to decrease despite adequate volume resuscitation and appropriate vasopressor therapy.
A case report of a child with acute lymphoblastic leukemia who had septic shock caused by Escherichia Coli in which we have used a continuous perfusion of nitroglycerin, is presented. The authors also describe their experience in the use of vasoactive drugs, namely vasodilators, in these kind of situations.
Keywords: Pediatric septic shock, acute lymphoblastic leukemia, vasoactive drugs, vasodilators.

Respiratory failure after continuos infusion of tramadol: a case report

Teresa Fontinhas, Luísa Gonçalves, Alexandre Carrilho

Summary:
The authors relate a clinical case of Pancreatitis with a respiratory depression after continuous infusion of tramadol. They review the possible causes, as well as similar cases existing in international publications.
Keywords: Tramadol; Continuous infusion; Respiratory depression.

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